Training

 

Acquiring & Purchasing Controlled Substances

The Unit for Laboratory Animal Medicine will continue to supply controlled substances to Principal Investigators until January 1, 2010 

Acquisition Sources of Controlled Substances after January 1, 2010

  • UMHS Inpatient B2 Pharmacy
  • Commercial distributors or vendors
    • Henry Schein – Veterinary Division
    • Butler Animal Health
    • Sigma-Aldrich (controlled substance chemicals and precursors)
    • Vortech Pharmaceuticals (Euthanasia Solution)
  • National Institute of Drug Abuse (NIDA)

Only Individual Registrants, Departmental Registrants, or authorized users with Power of Attorney can order controlled substances to be used in research.

UMHS Inpatient Pharmacy only stocks human pharmaceutical controlled substances, which are suitable for veterinary or animal research purposes. Telazol and euthanasia solutions must be ordered through a vendor that supplies veterinary controlled substances such as Henry Schein, Butler Animal Health, or Vortech Pharmaceuticals. Controlled substance chemicals may be ordered through Sigma-Aldrich (analytical or chemical research).

To avoid diversion or inappropriate use of a registrant’s DEA registration number, do not use as a purchase order number or as an identification number. Only provide a DEA registration number or a DEA Certificate of Registration copy to known vendors or the UMHS B2 Pharmacy.  

Commonly Used Controlled Substance Pharmaceutical Agents supplied by UMHS B2 Pharmacy and Vendors

UMHS Inpatient Pharmacy-Level B2

  • Registrants or a Power of Attorney must complete a Departmental Requisition-University Hospital Form. The Registrant DEA number, telephone contact number, and departmental short-code must be present on the form. A copy of the registrant’s current DEA Certificate of Registration (Form 223) must be presented or be on file with the UMHS B2 Inpatient Pharmacy.
  • When ordering Schedule II controlled substances, a DEA Form 222 (See UMHS B2 Pharmacy Sample DEA Form 222) must be completed and a copy must be faxed to the UMHS B2 Pharmacy. The original attached copies (1and 2) must be submitted with the requisition to the UMHS Inpatient B2 Pharmacy at the time of pick-up.
  • Registrants should allow 24 hours for order processing after orders are submitted. Authorized users may sign for and pick up orders at the UMHS Inpatient B2 pharmacy Monday-Friday from 0700-1300. University of Michigan photo identification must be presented. Authorized users must verify contents of each order prior to signing for pick up. Sign and date the requisition form. File a copy of the requisition form with inventory records.
  • Secure and update all newly received controlled substances into the laboratory general inventory upon delivery. Complete copy 3, DEA Form 222 if receiving Schedule II controlled substances. Update DEA Form 222 Usage Log if utilizing to track DEA 222 forms.

UMHS B2 Pharmacy Sample DEA Form 222

Commercial Distributors or Vendors

The University of Michigan has negotiated University pricing and has contracts with several commercial distributors or vendors to supply controlled substance pharmaceuticals or chemicals.

  • The “Shipping To” name and laboratory address (including room number) must exactly match the address listed on the DEA Certificate of Registration (Form 223).
    • A telephone contact number must be included on all orders.
    • Fax or mail the order invoice with a purchase order number, a copy of the Power of Attorney, and a copy of the DEA Certificate of Registration (Form 223) to the vendor.
    • For Schedule II substances, complete DEA Form 222 and mail attached copies (1 and 2) to the vendor. Vendors may require a copy faxed to them before mailing the original attached copies (1 and 2). Allow one week for processing time.
    • Controlled substance orders must use a shipping company that offers online tracking. Controlled substance orders must be delivered directly to an authorized user in the laboratory. Controlled substance packages cannot be left out in a hallway with other packages or be delivered to non-authorized users.
    • Count and verify contents of all vendor shipments received. Immediately report discrepancies or damaged items to the supplier. Sign and date the packing slip or shipping invoice. File packing slip/shipping invoice and request form with inventory records.
    • Secure and update all newly received controlled substances into the general inventory upon delivery. Complete copy 3, DEA Form 222 if receiving Schedule II controlled substances from outside vendors or suppliers. Update DEA Form 222 Usage Log if utilizing to track DEA 222 forms.

National Institute of Drug Abuse (NIDA)

  • Registrants can contract with the National Institute of Drug Abuse Drug Supply Program to acquire controlled substances.
  • Registrants must provide the following to NIDA for initial contracts:
    • Curriculum vitae and contact information.
    • UCUCA approval letter.
    • Protocol and justification including study numbers.
  • Drugs to be acquired from NIDA must be listed on or added to a Departmental or Individual Registrant’s State of Michigan Controlled Substance Research License and DEA registration
    • Allow 4-8 weeks for processing unlisted controlled substances.
    • NIDA will contact the DEA and State of Michigan for verification.
  • NIDA restricts controlled substance order quantities to less than a six month supply. Allow 30 days for processing orders.
  • NIDA orders for Schedule I or II controlled substances will require a DEA Form 222 to be completed and mailed. The address on the DEA Certificate of Registration (DEA Form 223) must match the address on DEA 222 Forms.  
  • Registrants must sign, date, and mail the enclosed “Shipment Received Notice” to NIDA upon delivery of an order. Failure to do so will result in NIDA refusing future orders or closing the account. File shipment receipts with inventory records.
  • Secure and update all newly received controlled substances into the perpetual inventory upon delivery. Complete copy 3, DEA Form 222 if receiving Schedule I or II controlled substances. Update DEA Form 222 Usage Log if utilizing to track DEA 222 forms.

DEA 222 Form Instructions

DEA 222 Form Usage Log

Power of Attorney Information

Power of Attorney Form